Two sample MR report
ABRACL_Alveolar Macrophages against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | 0.0034858 | 0.0793640 | 0.9666670 |
| Weighted median | 7 | -0.0361245 | 0.0145180 | 0.0128371 |
| Inverse variance weighted | 7 | -0.0342609 | 0.0117327 | 0.0034989 |
| Simple mode | 7 | -0.0404160 | 0.0212889 | 0.1063974 |
| Weighted mode | 7 | -0.0385516 | 0.0199791 | 0.1019020 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.182907 | 5 | 0.9465067 |
| Inverse variance weighted | 1.414170 | 6 | 0.9649908 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0229711 | 0.0477671 | 0.6508945 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001205 | 0 | TRUE | 0.2980429 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
